sonic hedgehog — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22089	HPI 1		Hedgehog/Smoothened
	HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced a...		Hedgehog/Smoothened
T26899	BRD50837	BRD-50837,BRD 50837
	BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T26901	BRD-9526	BRD 9526
	BRD-9526 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T25918	Palmitoyl-L-aspartic acid	L-N-Palmitoylaspartic acid
	Palmitoyl-L-aspartic acid is a natural N-acylaspartate that suppresses Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog. It does not alter the activity of cannabinoid rec...
T23307	SANT 2	SANT-2	Others
	SANT-2 is an inhibitor of Sonic hedgehog signaling and also antagonizes smoothened receptor activity (KD = 12 nM).		Others
T35538	HPI-1 (hydrate)	HPI-1 hydrate
	HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 μM) without significantly affecting Wnt signaling (IC50≥ 30 μM).1HPI-1 suppresses Hh activation induced by loss o...
T35940	Darinaparsin	Dimethylarsinic glutathione,Darinaparsin
	Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 &#181M) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 &#181M)...

Compounds

HPI 1

T22089

Synonym:

Target: Hedgehog/Smoothened

BRD50837

T26899

Synonym: BRD-50837,BRD 50837

Palmitoyl-L-aspartic acid

T25918

Synonym: L-N-Palmitoylaspartic acid

Synonym: HPI-1 hydrate

Target:

Darinaparsin

T35940

Synonym: Dimethylarsinic glutathione,Darinaparsin

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03345	Sonic Hedgehog Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Sonic Hedgehog Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q62226.
TMPJ-01170	SHH Protein, Mouse, Recombinant	Mouse	E. coli
	SHH Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20 KDa and the accession number is Q62226.
TMPJ-01127	SHH Protein, Human, Recombinant	Human	E. coli
	SHH Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19 KDa and the accession number is Q15465.
TMPJ-01171	SHH Protein, Mouse, Recombinant (C25II)	Mouse	E. coli
	SHH Protein, Mouse, Recombinant (C25II) is expressed in E. coli expression system. The predicted molecular weight is 18-20 KDa and the accession number is Q62226.
TMPJ-01128	SHH Protein, Human, Recombinant (C24II)	Human	E. coli
	SHH Protein, Human, Recombinant (C24II) is expressed in E. coli expression system. The predicted molecular weight is 20 KDa and the accession number is Q15465.
TMPY-02832	SHH Protein, Human, Recombinant (aa 198-462, His)	Human	HEK293 Cells
	SHH Protein, Human, Recombinant (aa 198-462, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is Q15465.
TMPY-02905	SHH Protein, Human, Recombinant (aa 1-197, His)	Human	HEK293 Cells
	SHH Protein, Human, Recombinant (aa 1-197, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q15465.
TMPY-02384	MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)	Human	E. coli
	MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expr...